Scoring of mucosa epithelium erosion and hemorrhagic, as qualitative data, was analyzed by Kruskall-Wallis test and continued by using Z test. Each gastric specimen was processed and histopathological changes were observed. Afterwards, they were given Indometachin emultion 5 mg/150 g BW once on 10th day. Positive control (K+) was given 0.5 ml CMC Na 0.5% for 9 days and then given Indomethacin emultion 5 mg/0.5 ml/150 g BW once on 10th day, and the other groups were given Ambon banana stem extract for (P1) 20 mg/150 g BW, (P2) 40 mg/150 g BW and (P3) 80 mg/150 g BW for 9 days. Negative control (K-) was given 0.5 ml CMC Na 0.5 % for 9 days and 0.5 ml corn oil was given on 10th. They were selected randomly and divided into five groups. This research used 30 male rats age 8-12 week having 150 gram weight. sapientum) to prevent gastric damage and observe histopathology of rat’s gastric induced by indomethacin. This research aims to find out the administration effect of Ambon banana stem extract (Musa paradisiaca var.
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